You may be asking yourself which certification track you should focus on. If you are already in a set career path, like network engineering or system administration, then your best bet is to select something from your given area of expertise. Cisco's track for networking or microsoft's track for systems administration are rock solid.
If you are interested in taking any direction with your career or are looking for some change, take a look at certification magazines annual certification salary survey to get some ideas. The highest paid certifications are typically some of the hardest to earn, but if you really want to change your careers direction, you are bound to ride the wave with a high paying cert.
Here's a link: Certification Magazine's 2009 Salary Survey